Method for purifying factor viii and preparations obtained

Details Method for purifying factor viii and preparations obtained Method for purifying factor viii and preparations obtained

C - Chemistry, Metallurgy

07

K

C07K 14/755 (2006.01) A61K 35/16 (2006.01) A61K 38/37 (2006.01)

Patent

CA 2077888

ABSTRACT. Method for purifying factor VIII and preparations obtained. In the method for purifying factor VIII from cryoprecipitate, which is dissolved and then treated with alumina gel in the customary manner, - the extract is diluted to a protein concentration not exceeding approximately 5 g/l, in particular 4 g/l, and subjected to viral inactivation with solvent/ detergent, - the inactivated extract containing the solvent/ detergent is then subjected to chromatography on a weak anion exchange column which is hydrophilic in nature, - the factor VIII then being eluted with a dissociat- ing buffer. Preparation obtained, having an activity of the order of at least 100 IU VIII:C/mg of protein.

Affiliated with

Also associated with

Rating

Method for purifying factor viii and preparations obtained does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for purifying factor viii and preparations obtained, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for purifying factor viii and preparations obtained will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1539876