C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/59 (2006.01) C07K 1/22 (2006.01)
Patent
CA 2290211
The present invention provides a method for purifying follicle stimulating hormone (FSH) from biological samples, for example, from human pituitary glands or human postmenopausal urine, wherein the FSH is contaminated with other proteins, by use of dye-ligand affinity chromatography (DAC). Depending on the starting material used and the initial purity of FSH in the starting material, additional purification steps may be employed. These steps preferably involve the use of hydrophobic interaction chromatography. This process may be used to generate affinity pure FSH suitable for therapeutic applications. The methods of the invention provide high purity FSH with high overall yield. A further advantage is the ability to easily regenerate the chromatography media for re-use, thus providing added economy to the purification process.
Musick James R.
Van Horn Erik
Smart & Biggar
Vitro Diagnostics Inc.
LandOfFree
Method for purifying fsh does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for purifying fsh, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for purifying fsh will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1870279