Method for purifying xylanase

C - Chemistry – Metallurgy – 12 – N

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195/123, 195/78

C12N 9/42 (2006.01) C07K 3/26 (1990.01)

Patent

CA 1283877

ABSTRACT OF THE DISCLOSURE The separation of xylanases from mixtures thereof with other hemcellulases, particulary cellulase produced by the cul- turing of hemicellulolytic microorganisms, particularly the fungus Trichoderma harzianum E58 and Trichoderma reesei by ultrafiltration through an ultrafiltration membrane having a low molecular weight cut-off point in the range of about 1,000 to 20,000 daltons to obtain a cellulase rich retentate and xylanase rich ultrafiltrate. The dilute xylanase rich filtrate from the ultrafiltration is concentrated and purified by adsorption and elution from an insoluble matrix, e.g. a cationic exchange resin. The xylanase obtained is suitable for use in the hydro- lysis of hemicellulose for which it is selective, particularly in the presence of cellulose and the cellulase rich retentate is suitable for the hydrolysis of cellulose.

558529

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