C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) G01N 33/564 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2164374
The present invention relates to a polyclonal antibody or a monoclonal antibody which is obtained by using, as the immunogen, a synthetic peptide having the following sequence (a part of which may be modified or deleted) or a soluble Fas antigen containing an intracellular region. Cys-Asn-Ile-Thr-Ser-Asp-Ser-Gln-Asn-Ser-Asn-Phe-Arg- Asn-Glu-Ile-Gln-Ser-Leu-Val These antibodies specifically recognize the intracellular region of a Fas antigen. By measuring a Fas antigen according to sandwich ELISA using any of these antibodies, it is possible to diagnose autoimmune diseases such as SLE, RA, etc.
Arai Hideo
Nakata Motomi
Okumura Ko
Yagita Hideo
Oriental Yeast Co. Ltd.
Riches Mckenzie & Herbert Llp
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