Method for radiolabeling proteins

Details Method for radiolabeling proteins Method for radiolabeling proteins

C - Chemistry, Metallurgy

07

K

530/3, 167/47, 5

C07K 1/13 (2006.01) A61K 51/08 (2006.01) A61K 51/10 (2006.01)

Patent

CA 1340167

A protein containing at least one pendant sulfhydryl group is directly radiolabeled with a radiometal which binds tightly to sulfhydryl groups, using one or more pendant sulfhydryl groups on the protein as endogenous ligands and optionally using an exogenous ligand which binds tightly to the radiometal ion to further stabilize the chelate.

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