Method for reconstructing a non-human mammal embryo with...

Details Method for reconstructing a non-human mammal embryo with... Method for reconstructing a non-human mammal embryo with...

A - Human Necessities

01

K

A01K 67/027 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2386105

The invention concerns the reconstruction in vitro of non-human mammal embryos by a method which consists in treating the nucleus of a somatic donor cell prior to its transfer into a receiver cytoplasm, said treatment comprising controlled proteolysis of non-histone proteins, and inducing an isomorphic swelling of said nucleus.

L'invention est relative à la reconstitution in vitro d'embryons de mammifères non humains par une méthode comprenant le traitement du noyau d'une cellule donneuse somatique préalablement à son transfert dans un cytoplasme receveur, ledit traitement comprenant la protéolyse ménagée des protéines non-histones, et l'induction d'un gonflement isomorphe dudit noyau.

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