Method for recovering a basic amino acid from a fermentation...

C - Chemistry – Metallurgy – 12 – P

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C12P 13/04 (2006.01) C07C 227/40 (2006.01) C07C 229/02 (2006.01)

Patent

CA 2604556

The invention relates to a method for recovering a basic amino acid from the fermentation liquor of a micro-organism strain that produces the basic amino acid. According to said method: a) the fermentation liquor is acidified with an acid, whose pKs value in water at 25 ~C ranges between 2 and 5; and b) the basic amino acid is separated from the aqueous liquor obtained in step a) by the successive charging of a single or multiple stage, serial arrangement of a strongly acidic cation exchanger in the form of a salt with the liquor that has been obtained in step a) and the subsequent elution of the basic amino acid using a basic eluant.

La présente invention concerne un procédé pour extraire un acide aminé basique du bouillon de fermentation d'une souche de micro-organisme produisant l'acide aminé basique. Ce procédé consiste a) à acidifier le bouillon de fermentation avec un acide dont la valeur pKs dans l'eau à 25 °C est comprise entre 2 et 5 puis b) à séparer l'acide aminé basique du bouillon aqueux obtenu à l'étape a), en chargeant successivement un ensemble sériel mono- ou multiétagé d'un échangeur de cations fortement acide sous forme ionique en bouillon obtenu à l'étape a) et en éluant l'acide aminé basique avec un éluant basique.

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