Method for recovering recombinant proteins

Details Method for recovering recombinant proteins Method for recovering recombinant proteins

C - Chemistry, Metallurgy

12

P

C12P 21/02 (2006.01) C07K 1/30 (2006.01) C07K 14/61 (2006.01)

Patent

CA 2060505

A method for recovering a recombinant protein from a protein solution containing high molecular weight contaminating proteins by directly adding amine or quaternary ammonium compounds to the solution in amounts sufficient to selectively pre- cipitate the high molecular weight protein contaminants. The high molecular weight precipitates are removed and the solution is further processed to remove low molecular weight contaminating proteins and other non-protein contaminants. The recombinant protein is subsequently recovered and further processed to produce a protein composition suitable for its intended use.

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