Method for reducing levels of c-reactive protein

Details Method for reducing levels of c-reactive protein Method for reducing levels of c-reactive protein

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 39/395 (2006.01) C12N 5/20 (2006.01)

Patent

CA 2517037

A compound comprising at least a structural entity which binds C-reactive protein (CRP) or parts of it or CRP in its monomeric, pentameric or multimeric form, preferably human CRP and which a.) blocks one or more CRP functions on cell surfaces or in a solution, preferably blood or other body fluids or from tissues, most preferably in vivo, b.) and/or depletes CRP from a solution, preferably blood or other body fluids or from tissues, most preferably in vivo.

L'invention concerne un composé comprenant au moins une entité structurelle qui se lie à une protéine C-réactive (CRP) ou à des parties de la protéine ou CRP sous sa forme monomère, pentamère ou multimère, de préférence, une protéine C-réactive humaine. Cette entité a) bloque au moins une fonction CRP sur des surfaces cellulaires ou dans une solution, de préférence, le sang ou d'autres fluides corporels ou provenant de tissus, idéalement, in vivo, b) et/ou diminuer la protéine C-réactive (CRP) provenant d'une solution, de préférence, du sang ou d'autres fluides corporels ou provenant de tissus, idéalement in vivo.

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