Method for relative quantitation of chromosomal dna copy...

Details Method for relative quantitation of chromosomal dna copy... Method for relative quantitation of chromosomal dna copy...

C - Chemistry, Metallurgy

40

B

C40B 40/06 (2006.01) C12N 5/073 (2010.01) C12N 5/0735 (2010.01) A01K 67/02 (2006.01) A61K 35/54 (2006.01) C12Q 1/68 (2006.01) C40B 50/14 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2707296

The present invention is directed to methods for determining the presence or absence of a genetic defect in an IVF embryo prior to transfer comprising performing real-time PCR and 2-.DELTA..DELTA.C T analyses to determine normalized copy number of at least one invariant locus on at least one chromosome collected from at least one cell of the embryo and selecting a candidate IVF embryo determined to be without genetic defect for transfer.

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