A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 1/34 (2006.01) A61M 1/38 (2006.01)
Patent
CA 2516403
The present invention relates to a method for using lectins that bind to pathogens having high mannose surface glycoproteins or fragments thereof which contain high mannose glycoproteins, to remove them from infected blood or plasma in an extracorporeal setting. Accordingly, the present invention provides a method for reducing viral load in an individual comprising the steps of obtaining blood or plasma from the individual, passing the blood or plasma through a porous hollow fiber membrane wherein lectin molecules are immobilized within the porous exterior portion of the membrane, collecting pass-through blood or plasma and reinfusing the pass-through blood or plasma into the individual.
La présente invention concerne un procédé pour utiliser des lectines qui se lient aux pathogènes comportant des glycoprotéines à surface de mannose élevée ou leurs fragments qui contiennent des glycoprotéines à mannose élevée, pour les supprimer dans le sang ou le plasma infecté, au moyen d'un dispositif extracorporel. Cette invention concerne aussi un procédé pour réduire la charge virale chez un individu, qui consiste à obtenir le sang ou le plasma de l'individu, à faire passer le sang ou le plasma à travers une membrane poreuse à fibres creuses, les molécules de lectine étant immobilisées à l'intérieur de la partie extérieure poreuse de la membrane, à collecter le sang ou le plasma soumis à ce traitement et à perfuser de nouveau le sang ou le plasma à l'individu.
Aethlon Medical Inc.
Gowan Intellectual Property
LandOfFree
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