A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/785 (2006.01) A61K 31/787 (2006.01) C08F 226/02 (2006.01) C08F 226/04 (2006.01) C08F 226/06 (2006.01)
Patent
CA 2620406
Polymers and compositions utilizing such polymers are disclosed for treating hyperphosphatemia and other illnesses associated with elevated serum phosphate levels. Phosphate binding polymers, or a pharmaceutically acceptable salt of the polymers, comprise pendent groups extending from a backbone of the polymer. Each pendent group comprises at least two nitrogen-bearing functional groups which bind phosphate. Variations of such polymer and compositions are disclosed.
L'invention concerne des polymères et des compositions dans lesquelles sont utilisés ces polymères, destinés au traitement de l'hyperphosphatémie ou d'autres maladies associées à des taux élevés de phosphate dans le sérum. L'invention concerne plus précisément des polymères fixant le phosphate, ou un sel de qualité pharmaceutique de ces polymères, comprenant des groupes pendants qui s'étendent à partir d'un squelette du polymère. Chacun de ces groupes comprend au moins deux groupes fonctionnels à base d'azote fixant le phosphate. L'invention concerne également des variations de ce polymère et de ces compositions.
Dhal Pradeep K.
Holmes-Farley Stephen Randall
Huval Chad C.
Genzyme Corporation
Gowling Lafleur Henderson Llp
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