G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/50 (2006.01) C12Q 1/02 (2006.01) G01N 33/15 (2006.01)
Patent
CA 2726118
Methods for screening for compounds that inhibit neurodegeneration are presented. Shedding of APP can be a useful marker for neurodegeneration and compounds that inhibit shedding of APP are useful as inhibitors of neurodegeneration. Such compounds may be useful in treatment and/or prevention of various neurological diseases, disorders and neuronal damage and may enhance growth, regeneration or survival of mammalian neuronal cells or tissue.
Cette invention concerne des procédés de criblage permettant d'identifier des composés qui inhibent la neurodégénérescence. L'excrétion des APP peut être un marqueur utile pour la neurodégénérescence et les composés qui inhibent l'excrétion des APP sont utiles à titre d'inhibiteurs de neurodégénérescence. Ces composés peuvent être utiles pour traiter et/ou prévenir diverses maladies, troubles neurologiques, et lésions neuronales et peuvent stimuler la croissance, la régénération ou la survie de cellules neuronales mammaliennes ou celles d'un tissu.
Nikolaev Anatoly
Tessier-Lavigne Marc
Genentech Inc.
Smart & Biggar
LandOfFree
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