G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01)
Patent
CA 2692112
The invention relates to methods for screening for selective modulator of NF- .kappa.B pathway activation. The invention concerns methods for primary screening molecules that potentially modulate (activate or inhibit) the NF-.kappa.B pathway activation by identifying and selecting molecules modulate the interaction of NEMO with other proteins. The invention also concerns methods for secondary screening for modulator (activator or inhibitor) of the NF- .kappa.B pathway activation.
La présente invention concerne des procédés de criblage pour modulateur sélectif de l'activation de la voie de signalisation NF-?B. L'invention concerne des procédés permettant le criblage primaire de molécules de modulation potentielle (activation ou inhibition) de l'activation de la voie de signalisation NF-?B par l'identification et la sélection de molécules de modulation de l'interaction de NEMO avec d'autres protéines. L'invention concerne également des procédés permettant le criblage secondaire pour un modulateur (activateur ou inhibiteur) de l'activation de la voie de signalisation NF-?B.
Agou Fabrice
Baleux Francoise
Chiaravalli Jeanne
Coic Yves-Marie
Israel Alain
Centre National de La Recherche Scientifique
Fasken Martineau Dumoulin Llp
Institut Pasteur
LandOfFree
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