Method for screening mobile phases in chromatography systems

Details Method for screening mobile phases in chromatography systems Method for screening mobile phases in chromatography systems

G - Physics

01

N

G01N 30/34 (2006.01)

Patent

CA 2689214

A method and system of screening or selecting a mobile phase eluent for a chromatography column is provided. A sample for chromatographic analysis or purification is combined with a solvent and passed through a membrane. A pressure measurement is taken of the sample/solvent combination in the system prior to the membrane. The pressure measurement may be compared to a second pressure and an appropriate solvent may be selected based on the relationship between the first measured pressure and the second pressure.

L'invention concerne un procédé et un système de criblage ou de sélection d'un éluent de phase mobile pour une colonne de chromatographie. Un échantillon pour analyse ou purification chromatographique est mélangé avec un solvant et passé au travers d'une membrane. La pression du mélange échantillon/solvant est mesurée dans le système avant la membrane. La mesure de pression peut être comparée à une seconde pression et un solvant approprié peut être sélectionné en fonction de la relation entre la première pression mesurée et la seconde pression.

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