Method for searching steroid sulfatase inhibitors

Details Method for searching steroid sulfatase inhibitors Method for searching steroid sulfatase inhibitors

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 9/16 (2006.01) C12N 9/99 (2006.01) C12N 15/55 (2006.01) C12Q 1/34 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2324424

A method for efficiently searching compounds capable of inhibiting steroid sulfatase activity and thus being useful in treating hormone-dependent diseases such as mammary cancer which comprises treating cells having a steroid sulfatase gene transferred thereinto with the compounds to be tested and then judging the proliferation of the cells.

Procédé servant à rechercher des composés capables d'inhiber l'activité de stéroïde sulfatase et, de ce fait, utiles pour traiter des maladies de dépendance hormonale, telles que le cancer mammaire, ce qui consiste à traiter des cellules dans lesquelles a été transféré un gène de stéroïde sulfatase, au moyen des composés à tester, puis à évaluer la prolifération de ces cellules.

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