Method for selectively increasing the ratio of single major...

Details Method for selectively increasing the ratio of single major... Method for selectively increasing the ratio of single major...

C - Chemistry, Metallurgy

12

P

195/89

C12P 1/06 (2006.01) C07K 9/00 (2006.01) C12P 21/06 (2006.01)

Patent

CA 1249785

ABSTRACT METHOD FOR SELECTIVELY INCREASING THE RATIO OF SINGLE MAJOR COMPONENTS OF TEICOPLANIN A2 COMPLEX The object of this invention is to provide a method for selectively increasing the ratio of the single T-A2 major components in the T-A2 complex. More particularly, the object of this invention is a process for obtaining teicoplanin A2 selectively enriched in any of its major components T-A2-1, T-A2-2, T-A2-3, T-A2-4 and T-A2-5 which consists in adding to the culture medium of Actinoplanes teichomyceticus nov. sp. ATCC 31121 or a mutant thereof which produces T-A2 complex through the same metabolic pathway, a selectively effective amount of an appropriate precursor.

509462

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