Method for separating a basic amino acid from fermentation...

Details Method for separating a basic amino acid from fermentation... Method for separating a basic amino acid from fermentation...

C - Chemistry, Metallurgy

07

C

C07C 227/40 (2006.01) C07C 229/26 (2006.01)

Patent

CA 2404442

This invention relates to a method for separating basic amino acids from fermentation broth comprising contacting the broth with strong acid cation exchange resins that have a low degree of cross-linkage and eluting the amino acid. The method described herein results in higher yield and higher purity of lysine, in addition to higher throughput, as compared to conventional processes of purification of lysine from fermentation broth.

La présente invention concerne un procédé de séparation d'acides aminés basiques à partir d'un bouillon de fermentation. Ce procédé consiste à mettre le bouillon en contact avec des résines échangeuses de cations d'acide fort, qui présentent un faible degré de réticulation, puis à éluer l'acide aminé. Ce procédé permet d'obtenir des rendements plus élevés et une plus grande pureté de lysine, en plus d'un plus grand débit, par comparaison à des procédés classiques de purification de lysine à partir de bouillon de fermentation.

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