Method for separating and purifying protein antigens from...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/235 (2006.01) A61K 39/10 (2006.01) B01D 15/08 (2006.01) B01J 20/22 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1295985

PRECIS DE LA DIVULGATION: L'invention concerne un procédé de purification des antigènes protéiques des bactéries du genre Bordetella, caractérisé par le fait qu'il consiste à mettre en contact une solution contenant lesdits antigènes protéiques avec un matériau de chromatographie d'affinité constitué par un support solide sur lequel est fixé un ligand ayant une affinité pour la toxine pertussis, ledit ligand étant une protéine désialylée choisie parmi la fétuine désialylée et l'haptoglobine desialylée, puis a recueillir ou à éluer les antigènes recherchés.

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