G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/555 (2006.01) C12N 5/078 (2010.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2375115
The present invention relates to methods for separating cells using immunorosettes. The method involves contacting a sample containing nucleated cells and red blood cells with an antibody composition which allows immunorosettes of the nucleated cells and the red blood cells to form. The antibody composition preferably contains bifunctional antibodies or tetrameric antibody complexes.
La présente invention concerne un procédé de séparation des cellules par utilisation de rosettes immunitaires. En l'occurrence, on prend un échantillon contenant des cellules nucléées et des érythrocytes, et on le met en contact avec une composition anticorps. Il en résulte la formation de rosettes immunitaires des cellules nucléées et des érythrocytes. La composition anticorps contient de préférence des anticorps bifonctionnels ou des complexes anticorps tétramères.
Lansdorp Peter
Peters Carrie
Thomas Terry E.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Stemcell Technologies Inc.
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