Method for separating polypeptides

Details Method for separating polypeptides Method for separating polypeptides

C - Chemistry, Metallurgy

07

K

530/7.04, 530/1.

C07K 7/04 (2006.01) C07K 1/32 (2006.01)

Patent

CA 1255849

07/-21-241 METHOD FOR SEPARATING POLYPEPTIDES ABSTRACT A method of separating a first polypeptide fraction from a second polypeptide fraction of a mixed solution is disclosed. A predetermined charged polymer is admixed with the mixed solution preferably in the presence of a neutral polymer. The charged polymer interacts with the first fraction to form a precipitate. The neutral polymer enhances the effectiveness of the charged polymer in precipitating the first fraction. By proper selection of the polymer combination the desired polypeptide fraction can be precipitated from solution leaving the other polypeptide fraction in solution or vice versa.

494022

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