Method for sequencing peptides and proteins using...

Details Method for sequencing peptides and proteins using... Method for sequencing peptides and proteins using...

B - Operations, Transporting

01

J

B01J 19/08 (2006.01) G01N 27/00 (2006.01) H01J 49/14 (2006.01) H01J 49/42 (2006.01)

Patent

CA 2654059

Methods for fragmentation of large molecular ions, including proteins, nucleic acids, dendromers, and nanomaterials, compatible with several mass spectrometric techiniques. The methods involve providing a gas-phase ion and allowing the gas phase ion to undergo collisions with metastable states of noble gases or nitrogen gas.

L'invention concerne des procédés de fragmentation de gros ions moléculaires, notamment des protéines, des acides nucléiques, des dendromères et des nanomatériaux, compatibles avec plusieurs techniques de spectrométrie de masse. Les procédés selon l'invention consistent à obtenir un ion en phase gazeuse et à permettre à cet ion en phase gazeuse de subir des collisions avec des états métastables de gaz nobles et d'azote gazeux.

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