Method for silk fibroin gelation using sonication

Details Method for silk fibroin gelation using sonication Method for silk fibroin gelation using sonication

A - Human Necessities

61

K

A61K 47/42 (2006.01) A61K 35/64 (2006.01)

Patent

CA 2688431

This invention provides for a process of rapidly forming silk fibroin gelation through ultrasonication. Under the appropriate conditions, gelation can be controlled to occur within two hours after the ultrasonication treatment. Biological materials, including viable cells, or therapeutic agents can be encapsulated in the hydrogels formed from the process and be used as delivery vehicles.

La présente invention concerne un procédé permettant de parvenir rapidement à la gélification de fibroïne de soie par sonication aux ultrasons. Dans les conditions appropriées, la gélification peut être régulée de manière à se produire deux heures après le traitement de sonication aux ultrasons. Des matières biologiques, y compris des cellules viables, ou des agents thérapeutiques peuvent être encapsulés dans des hydrogels obtenus à partir du procédé et servir de véhicule d'administration.

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