Method for sleep induction

A - Human Necessities – 61 – K

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A61K 31/16 (2006.01) C07C 231/24 (2006.01)

Patent

CA 2200208

Sleep may be induced by administration of fatty acid primary amides, includes cis-9,10-octadecenoamide. Furthermore, sleep deprivation may be assayed by analyzing cerebrospinal fluid with respect to the presence of fatty acid primary amides, including cis-9,10-octadecenoamide. The presence of cis-9,10- octadecenoamide in cerebrospinal fluid is correlated with comparative sleep deprivation.

Induction du sommeil par administration d'amides primaires d'acides gras, et notamment de cis-9,10-octadécénoamide. On peut également évaluer le manque de sommeil par analyse du liquide céphalo-rachidien sur le plan de la présence d'amides primaires d'acides gras, et notamment de cis-9,10-octadécénoamide. La présence de cis-9,10-octadécénoamide dans le liquide céphalo-rachidien est en corrélation avec un manque de sommeil relatif.

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