C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/61 (2006.01)
Patent
CA 2276252
A method for the solubilization and/or naturation of a somatotropin involves contacting a somatotropin with a detergent composition and water under conditions effective to obtain a naturated somatotropin, wherein the detergent composition may be a C10, C12, C16 or C18 acyl glutamate, a C10, C14 or C18 alkyl sulfate, an alcohol ethoxy sulfate, lauroyl ethylenediamine-triacetic acid (LEDA), a C10 to C18 linear alkyl benzene sulfonate, diphenyl disulfonate or an acyl amino acid.
La présente invention concerne un procédé utilisé pour la solubilisation et/ou la naturation d'une somatotrophine. Ce procédé implique la mise en contact d'une somatotrophine avec une composition détergente et de l'eau, dans des conditions effectives afin d'obtenir une somatotrophine naturée dans laquelle la composition du détergeant peut être un acyle glutamique en C¿10?, C¿12?, C¿16? ou C¿18?, un alkyl-sulfate en C¿10?, C¿14? ou C¿18?, un éthoxy sulfate d'alcool, un lauroyl éthylenediamine - acide triacétique (LEDA), un alkyle benzène sulfonate linéaire en C¿10? à C¿18?, un diphényle disulfonate ou un acide acylaminé.
Ballinger Jessica Marie
Storrs S. Bradley
Tou Jacob S.
Mcfadden Fincham
Monsanto Company
Monsanto Technology Llc
LandOfFree
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