Method for solution phase synthesis of oligonucleotides

Details Method for solution phase synthesis of oligonucleotides Method for solution phase synthesis of oligonucleotides

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) B01J 19/00 (2006.01) C07C 43/225 (2006.01) C07C 43/23 (2006.01) C07C 57/03 (2006.01) C07C 57/13 (2006.01) C07C 59/60 (2006.01) C07D 207/452 (2006.01) C07D 209/48 (2006.01) C07F 7/12 (2006.01) C07H 19/04 (2006.01) C07H 19/06 (2006.01) C07H 19/16 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2234159

This invention discloses an improved method for the sequential solution phase synthesis of oligonucleotides. The method lends itself to automation and is ideally suited for large scale manufacture of oligonucleotides with high efficiency.

L'invention concerne un procédé amélioré permettant la synthèse séquentielle d'oligonucléotides en solution. Le procédé se prête à l'automation et convient parfaitement pour la fabrication d'oligonucléotides sur une grande échelle et avec un rendement élevé.

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