Method for specific immunoassay of human plasmatic...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/08 (2006.01) A61K 39/385 (2006.01) C07K 16/40 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2148268

Novel method for the assay of plasmatic glutathione peroxidase (pl.GPx) based on a specific immunoassay using antibodies directed against an oligopeptide selected from the pl.GPx sequence. The invention also concerns said oligopeptide and specific antibodies. Also disclosed is a kit for carrying out said method. Application in medical diagnosis and monitoring of the evolution of pathologies induced by a variation in pl.GPx concentration.

2148268 9506719 PCTABS00171 L'invention concerne une nouvelle méthode de dosage de la glutathion peroxydase plasmatique (pl.GPx) basée sur un immunodosage spécifique grâce à l'utilisation d'anticorps dirigés contre un oligopeptide choisi dans la séquence de la pl.GPx. L'invention couvre aussi l'oligopeptide et les anticorps spécifiques. L'invention concerne également un kit pour la mise en oeuvre de la méthode. L'invention s'applique au domaine du diagnostic médical et du suivi de l'évolution des pathologies liées à une variation de la concentration en pl.GPx.

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