A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/522 (2006.01) A61K 9/30 (2006.01) A61K 47/02 (2006.01) A61P 25/16 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) C07D 473/06 (2006.01)
Patent
CA 2540109
A method of stabilizing a diarylvinylene compound, e.g., one represented by the formula (I): (I) (wherein Y1 and Y2 are the same or different and each represents hydrogen, halogeno, or lower alkyl; and Z and A are the same or different and each represents (un)substituted aryl or (un)substituted heteroaryl), or a pharmacologically acceptable salt of the compound, the compound or salt being contained in a solid medical preparation, characterized by causing an inorganic substance and/or a colorant to be present in the solid medical preparation.
L'invention concerne un procédé de stabilisation d'un composé diarylvinylène, par ex. d'un composé représenté par la formule (I) dans laquelle Y?1¿ et Y?2¿ sont identiques ou différents et représentent hydrogène, halogéno ou alkyle inférieur, et Z et A sont identiques ou différents et représentent aryle substitué ou non ou hétéroaryle substitué ou non, ou un sel pharmaceutiquement acceptable de ce composé, lesdits composé ou sel étant contenus dans une préparation médicale solide. Le procédé selon l'invention est caractérisé en ce que ladite préparation médicale solide contient une substance inorganique et/ou un colorant.
Aimoto Masaharu
Ishikawa Yasuhiro
Kaji Kiichiro
Kaneko Naoki
Uchida Akihiro
Goudreau Gage Dubuc
Kyowa Hakko Kirin Co. Ltd.
Kyowa Hakko Kogyo Co. Ltd.
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