Method for stabilizing a tumor necrosis factor and a stable...

Details Method for stabilizing a tumor necrosis factor and a stable... Method for stabilizing a tumor necrosis factor and a stable...

A - Human Necessities

61

K

167/103.2

A61K 35/12 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) A61K 47/42 (2006.01)

Patent

CA 1187412

ABSTRACT OF THE DISCLOSURE A method for stabilizing a Tumor Necrosis Factor (TNF), which comprises adding at least one member selected from the group consisting of an albumin, a gelatin, a globulin, a protamine and a salt of protamine to an aqueous solution or powder containing TNF, and a stable aqueous solution or powder which contains TNF and an effective amount of such a protein. The aqueous solution or powder containing TNF can be stored for a prolonged period of time without losing its activity, and is stable on freezing, thawing, lyophilization or the like.

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