Method for stimulating an immune response

Details Method for stimulating an immune response Method for stimulating an immune response

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 38/17 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2213798

There is disclosed a method of stimulating an immune response comprising administering an effective amount of a CD40 binding protein. The method is useful in treating individuals infected with pathogenic or opportunistic organisms, and individuals having a depressed cellular immune response. CD40 binding proteins include CD40 ligand, monoclonal antibodies that specifically bind CD40, and combinations thereof.

L'invention décrit un procédé visant à stimuler une réponse immunitaire consistant à administrer une dose efficace d'une protéine de liaison CD40. Ledit procédé est utile dans le traitement de sujets infectés par des organismes pathogènes ou opportunistes ainsi que de sujets présentant une réponse immunitaire cellulaire déprimée. Les protéines de liaison CD40 comprennent le ligand CD40, des anticorps monoclonaux liant spécifiquement le CD40 et des combinaisons de ceux-ci.

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