Method for stimulating proliferation of peripheral blood...

Details Method for stimulating proliferation of peripheral blood... Method for stimulating proliferation of peripheral blood...

C - Chemistry, Metallurgy

12

N

195/46

C12N 5/08 (2006.01) C12N 5/06 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2021500

This invention relates to a selective method of proliferation of at least one of certain lymphocytic cellular subpopulations, particularly the CD4+, CD8+, and Natural Killer (NK) subpopulations, within a starting population of peripheral blood lymphocytes (PBL). A relatively small amount of a starting peripheral blood lymphocytic cellular population is cultured in a multi-step process, beginning with an anti-CD3 antibody immobilized to a culturing substrate.

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