Method for stimulation collagen synthesis and/or kgf expression

A - Human Necessities – 61 – K

Patent

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A61K 8/64 (2006.01)

Patent

CA 2596597

The present invention relates to a method for stimulating collagen synthesis and/or KGF expression, and more particularly, to a method for stimulating collagen synthesis and/or KGF expression using the AIMPl or its fragment. The AIMPl or its fragment can be effectively used for the stimulation of collagen synthesis and/or KGF expression in a subject in need thereof, the treatment of skin aging in the subject, the treatment of the flaccid and/or wrinkled skin in the subject, the promoting the smoothing and/or firming of the skin in the subject, the treatment of adverse cutaneous effects of menopause in the subject, and the treatment of adverse effects of menopause on the collagen.

La présente invention a trait à un procédé pour la stimulation de synthèse de collagène et/ou d'expression de facteur de croissance de kératinocytes (KGF), et plus particulièrement, à un procédé pour la stimulation de synthèse de collagène et/ou d'expression de KGF utilisant l'AIMP1 ou un fragment de celui-ci. L'AIMP1 ou son fragment peut être efficacement utilisé pour la stimulation de synthèse de collagène et/ou d'expression KGF chez un sujet qui en a besoin, pour le traitement du vieillissement de la peau chez le sujet, pour le traitement de peau flasque et/ou ridée chez le sujet, pour favoriser l'adoucissement et/ou le raffermissement de la peau chez le sujet, pour le traitement d'effets cutanés nuisibles de ménopause chez le sujet, et le traitement d'effets nuisibles de ménopause sur le collagène.

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