Method for studying enzymatic and other biochemical reactions

G - Physics – 01 – N

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324/44, 150/15.3

G01N 33/48 (2006.01) C12Q 1/00 (2006.01) G01N 27/22 (2006.01) G01N 33/487 (2006.01)

Patent

CA 1061230

Abstract of the Disclosure A method for studying enzymatic and other biochemical reactivity of a substance with a substrate specific for the biochemical reaction, which method comprises: providing a measuring device having electrodes coated with said substrate ant immersed ill a solution; determining the capacitance between said electrodes for the establishment of a control value; introducing said substance to said solution of the measuring device; and measuring the capaci- tance between said electrodes a second time to obtain a quantitative measure of the reactivity of the substance with said substrate. The method is parti- cularly suitable for the determination of enzyme activity of the type serin proteases.

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