Method for synthesizing procoagulant factor viii activity

A - Human Necessities – 61 – K

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195/39.1

A61K 35/16 (2006.01) A61K 33/32 (2006.01) A61K 35/14 (2006.01) C07K 14/755 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1182748

-16- METHOD FOR SYNTHESIZING PROCOAGULANT FACTOR VIII ACTIVITY Abstract of the Disclosure Disclosed herein is a method for synthesizing pro- coagulant factor VIII from inactive protein by incubating the protein in the presence of an effective amount for synthesizing procoagulant factor VIII of a manganese salt. The method is useful to synthesize AHF in plasma that has been collected with an anticoagulating agent.

390376

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