C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
150/13
C12Q 1/02 (2006.01) C12N 5/00 (2006.01) G01N 33/50 (2006.01)
Patent
CA 1261718
ABSTRACT An in vitro testing method for biocompatibility, particularly toxicological effect, of substances is based on the change in the time for closure of a disruption in a confluent cell culture caused by treatment with the substance. The method can be used to replace a substantial number of toxicity tests, including the Draize test for ocular irritancy.
507913
Jumblatt Marcia M.
Neufeld Arthur H.
Eye Research Institute Of The Retina Foundation
Riches Mckenzie & Herbert Llp
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