C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 49/00 (2006.01) A61P 9/00 (2006.01) A61P 35/00 (2006.01) C07D 209/30 (2006.01) C07D 209/42 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07K 14/705 (2006.01) C12Q 1/00 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) G01N 33/52 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) A61K 31/4025 (2006.01) A61K 31/404 (2006.01) A61K 31/4439 (2006.01) A61K 31/506 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2438427
A method for testing influence of a drug on integrin expression, which comprises the step of measuring an integrin expression amount in platelets of a patient to which the drug is administered and the step of determining influence of the drug on integrin expression in cells other than platelets based on the measured expression amount.
La présente invention concerne un procédé servant à analyser l'effet d'un médicament sur l'expression d'une intégrine, ledit procédé comprenant la mesure du taux d'expression de l'intégrine dans les plaquettes d'un patient auquel le médicament a été administré, et l'évaluation de l'effet du médicament sur l'expression de l'intégrine dans des cellules autres que les plaquettes, en se basant sur le taux d'expression ainsi mesuré.
Funahashi Yasuhiro
Hata Naoko
Ono Naoto
Senba Taro
Wakabayashi Toshiaki
Eisai Co. Ltd.
Eisai R&d Management Co. Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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