Method for testing the toxicity of chemical substances using...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/00 (2006.01) C12Q 1/32 (2006.01) C12Q 1/42 (2006.01)

Patent

CA 2339254

An in vivo and an in vitro toxicity test method is described using an organism or part of an organism from the class Gastropoda. The method is particularly useful for toxicity testing of chemical substances intended for application to human or animal mucosa, such as the intestinal, vaginal, buccal, nasal or respiratory mucosa. The test method may be used both as a screening test and also as a quantitative toxicity test suitable for ranking the toxicity of chemical substances.

L'invention concerne un procédé de test de toxicité in vivo et in vitro, ce procédé utilisant notamment un organisme, ou une partie d'un organisme, de la classe des gastéropodes. Le procédé de cette invention est particulièrement utile pour tester la toxicité de substances chimiques destinées à être appliquées sur une muqueuse humaine ou animale, par exemple la muqueuse intestinale, vaginale, buccale, nasale, ou respiratoire. Ce procédé de test peut être utilisé à la fois comme test de dépistage et comme test de toxicité quantitative, lequel est permet de classifier la toxicité desdites substances chimiques.

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