Method for the analysis of differential expression in...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) C40B 30/00 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/561 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) C07K 14/47 (2006.01) C12N 9/12 (2006.01) C12N 15/12 (2006.01) C12N 15/54 (2006.01)

Patent

CA 2635127

The invention relates to a method for the analysis of differential expression in colorectal cancer, which is based on the variation that occurs in patients affected by said disease in the expression levels of genes that encode proteins of the condensin complex and associated proteins. The aforementioned proteins can be used as markers for the diagnosis of said tumours as well as in the prevention and treatment of same.

L'invention concerne un procédé d'analyse d'expression différentielle dans le cancer colorectal basé sur la variation de niveaux d'expression des gènes qui codifient les protéines du complexe condensine et des protéines associées qui sont engendrées chez des patients souffrant de cette maladie et qui peuvent être utilisées en tant que marqueurs pour le diagnostic de ces tumeurs, ainsi que dans la prévention et le traitement de celles-ci.

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