A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 39/39 (2006.01) A61K 48/00 (2006.01) A61P 31/20 (2006.01) A61P 37/00 (2006.01) C12N 15/67 (2006.01)
Patent
CA 2310575
The present invention provides a method of increasing adenoviral gene expression in a tissue of an animal, comprising the step of administering to said animal a pharmacologically effective dose of tumor necrosis factor binding protein. Also provided are various methods of reducing an inflammatory response associated with adenoviral administration in a tissue of an animal, comprising the step of administering to said animal a pharmacologically effective dose of tumor necrosis factor binding protein.
La présente invention concerne un procédé d'augmentation de l'expression génique adénovirale, dans un tissu d'un animal, ce procédé consistant à administrer à cet animal une dose efficace sur le plan pharmacologique d'une protéine de fixation sur le facteur de nécrose tumorale. L'invention concerne également plusieurs procédés de réduction d'une réponse inflammatoire associée à l'administration adénovirale dans un tissu d'un animal, ces procédés comprenant l'étape consistant à administrer à cet animal une dose efficace sur le plan pharmacologique d'une protéine de fixation sur le facteur de nécrose tumorale.
Edwards Carl K.
Mountz John D.
Zhang Huang-Ge
Zhou Tong
Borden Ladner Gervais Llp
Uab Research Foundation
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