Method for the determination of a differential white blood...

G - Physics – 01 – N

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150/11, 150/3

G01N 33/49 (2006.01) G01N 33/50 (2006.01) G01N 1/30 (2006.01)

Patent

CA 1317533

ABSTRACT OF THE DISCLOSURE This invention relates to a method and composition for the rapid determination of a differential white blood cell count in a sample, which method comprises: a) preparing a reagent solution comprising formaldehyde or paraformaldehyde; a surfactant; a sugar or sugar alcohol; and a buffer; and b) rapidly mixing said reagent solution with the sample to be analyzed to form a reaction mixture, wherein both said reagent solution and said sample are initially at room temperature; and c) rapidly heating said reaction mixture to a temperature of from about 62°C to about 72°C in order to lyse the red blood cells in said sample and fix the white blood cells in said sample.

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