C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2632586
The present invention refers to a method for the in vitro or in vivo diagnosis of cardiovascular diseases, in particular high blood pressure, stenosis, vessel occlusion and/or other thrombotic events, wherein the nucleotide at position 950 of a nucleic acid coding for the human ARK2 protein or the amino acid at position 298 of the human ARK2 protein of a sample of a person is determined as well as to the use of ARK2 for the development and/or production of a medicament for treating a cardiovascular disease.
La présente invention concerne un procédé de diagnostic in vitro ou in vivo de maladies cardiovasculaires, en particulier l'hypertension, la sténose, l'occlusion vasculaire et/ou d'autres événements thrombotiques, le nucléotide en position 950 d'un acide nucléique codant pour la protéine ARK2 humaine ou l'acide aminé en position 298 de la protéine ARK2 humaine d'un échantillon d'un individu étant déterminé, ainsi que l'utilisation de l'ARK2 pour développer et/ou produire un médicament destiné à traiter une maladie cardiovasculaire.
Herrmann Matthias
Kozian Detlef
Leeuw Thomas
Maerz Winfried
Renner Wilfried
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis
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