G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01)
Patent
CA 2442708
The invention provides a method for the diagnosis of dementia and transmissible spongiform encephalopathies in a subject by detecting the levels of glycoproteins that bind wheat germ agglutinin. The invention also provides a method for diagnosis of dementia and transmissible spongiform encephalopathies in a subject by comparing the levels of glycoproteins that bind wheat germ agglutinin with the glycosylation patterns of biomarkers, acteylcholinesterase and butyrylcholinesterase.
L'invention concerne une méthode permettant de diagnostiquer la démence et les encéphalopathies spongiformes transmissibles chez un sujet par détection des niveaux de glycoprotéines se liant avec l'agglutinine du germe de blé. L'invention concerne également une méthode permettant de diagnostiquer la démence et les encéphalopathies spongiformes transmissibles chez un sujet par comparaison des niveaux de glycoprotéines se liant à l'agglutinine du germe de blé avec les motifs de glycosylation de biomarqueurs, de l'acétylcholinestérase et de la butyrylcholinestérase.
Fodero Lisa
Small David Henry
Axonyx Inc.
Monash University
Shapiro Cohen
LandOfFree
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