Method for the direct synthesis of oligorhamnosides,...

C - Chemistry – Metallurgy – 07 – H

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C07H 3/06 (2006.01) A61K 31/48 (2006.01) A61K 31/70 (2006.01) A61K 31/715 (2006.01) C07H 15/04 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2544361

The invention relates to a method of preparing oligorhamnosides, comprising a one-pot reaction in acetonitrile without any rhamnose protection or deprotection reaction. The invention also relates to a composition comprising a mixture of oligorhamnosides, which can be obtained using said method and which has between 2 and 12 rhamnose units. The invention further relates to a medicament comprising said composition, which is preferably intended to regulate inflammatory mechanisms, and to a cosmetic treatment method.

La présente invention concerne un procédé de préparation d'oligorhamnosides en une réaction « one-pot » dans l'acétonitrile, sans aucune réaction de protection ou de déprotectioh du rhamnose. Elle concerne également une composition comprenant un mélange d'oligorhamnosides, susceptible d'être obtenu par ce procédé, ayant 2 à 12 motifs rhamnose. Enfin, elle concerne un médicament comprenant cette composition, avantageusement destiné à réguler les mécanismes inflammatoires, et une méthode de traitement cosmétique.

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