Method for the enantioselective enzymatic reduction of keto...

Details Method for the enantioselective enzymatic reduction of keto... Method for the enantioselective enzymatic reduction of keto...

C - Chemistry, Metallurgy

12

P

C12P 7/02 (2006.01)

Patent

CA 2597648

The invention relates to a method for the enantioselective enzymatic reduction of keto compounds, more particularly of 4-halo-3-oxobutyric acid esters to produce the corresponding R-alcohols and S-4-halo-3-oxobutyric acid esters, using an R-specific oxidoreductase in the presence of a cofactor.

L'invention concerne un procédé de réduction enzymatique énantiosélective de composés cétoniques, en particulier d'esters de l'acide 4-halo-3-oxobutyrique, pour obtenir les R-alcools ou esters de l'acide S-4-halo-3-hydroxybutyrique correspondants, au moyen d'une oxydoréductase R-spécifique, en présence d'un cofacteur.

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