Method for the formation of ibuprofen crystals

Details Method for the formation of ibuprofen crystals Method for the formation of ibuprofen crystals

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 31/192 (2006.01)

Patent

CA 2464756

The invention relates to a method for the formation of ibuprofen crystals, characterised in that the solidification occurs after crystallisation by displacement, crystallisation by cooling, crystallisation by evaporation or a combination thereof in the presence of one or several additives and the use of the ibuprofen produced as above for pharmaceutical formulations.

La présente invention concerne un procédé pour former des cristaux de profènes, caractérisé en ce que la solidification est provoquée par un procédé de précipitation par déplacement, de cristallisation par refroidissement, de cristallisation par évaporation, ou par une combinaison de ces procédés, en présence d'un ou de plusieurs additifs. L'invention concerne par ailleurs l'utilisation des profènes ainsi produits dans des formulations pharmaceutiques.

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