Method for the identification of syntenic regions

Details Method for the identification of syntenic regions Method for the identification of syntenic regions

G - Physics

06

F

G06F 19/00 (2006.01)

Patent

CA 2518086

The identification of the syntenic regions of a given genomic fragment conventionally involves a similarity-based search, and then taking the best hits and extending them manually until the whole region of interest is covered. Such a process is labor intensive and not suitable for a pipeline with thousands of sequences to analyze. The present invention consists of a method for the automatic identification of syntenic regions of a given input sequence, and its optimization to yield results with high specificity.

L'identification classique de zones synténiques d'un fragment génomique donné consiste à effectuer une recherche basée sur la similarité et à prendre les meilleurs résultats pour les étendre manuellement et couvrir l'ensemble de la zone concernée. Un tel procédé demande beaucoup de travail et n'est pas adapté à une ligne comprenant des milliers de séquences à analyser. La présente invention concerne donc un procédé d'identification automatique de zones synténiques d'une séquence entrée déterminée, et son optimisation pour obtenir des résultats de haute spécificité.

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