G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 27/416 (2006.01) C12Q 1/68 (2006.01) G01N 27/02 (2006.01) G01N 27/22 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01)
Patent
CA 2432864
The invention relates to a method for detecting one or more analytes by using a recognition reaction, with the following steps - preparing a device with - a measurement electrode (1, 2) with a biofunctional surface, the biofunctional surface having recognition elements for the analytes, - one or more counterelectrodes (7), - a liquid electrolyte (8) between the measurement electrode (1, 2) and the counterelectrodes (7), - bringing analytes labelled with electrically active labelling units into contact with the biofunctional surface, the electrically active labelling units either having been bound to the analytes before contact of the analytes with the biofunctional surface or being bound to the analytes after contact of the analytes with the biofunctional surface, - applying a) a time-varying voltage or b) a time-varying current between the first counterelectrode (7) and the measurement electrode (2), and - either in case a) measuring the current or in case b) measuring the voltage between the first counterelectrode (7) and the measurement electrode (2), or - in case a) measuring the current or in case b) measuring the voltage between the second or another counterelectrode (7) and the measurement electrode (2). The invention furthermore relates to a device with which the method according to the invention can be carried out.
Burmeister Jens
Diessel Edgar
Hoheisel Werner
Kohler Burkhard
Merker Udo
Aktiengesellschaft Bayer
Fetherstonhaugh & Co.
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