Method for the in vitro diagnosis of stroke

Details Method for the in vitro diagnosis of stroke Method for the in vitro diagnosis of stroke

C - Chemistry, Metallurgy

07

K

C07K 14/58 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2732445

The present invention relates to a method for the in vitro diagnosis of stroke and transient ischemic attack (TIA) in an individual, comprising the following steps: (a) measuring the level of proBNP(1 -108), or of fragments of proBNP(1 -108) comprising a RAPRSP sequence (SEQ ID NO: 1 ), in a biological sample of the individual; (b) comparing the measured level with a cut-off value; (c) determining therefrom whether a stroke or a TIA has occurred in the individual.

Cette invention concerne une méthode de diagnostic in vitro de l'accident vasculaire cérébral et de laccident ischémique transitoire (AIT) chez un sujet, comprenant les étapes suivantes : (a) mesure du taux de proBNP(1 -108) ou de fragments de proBNP(1 -108) comprenant une séquence RAPRSP (SEQ ID NO: 1 ) dans un échantillon biologique du sujet; (b) comparaison du taux mesuré avec une valeur limite; (c) détermination, à partir de cette comparaison, de la survenue d'un accident vasculaire cérébral ou dun AIT chez le sujet.

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