Method for the isolation of haptoglobin

Details Method for the isolation of haptoglobin Method for the isolation of haptoglobin

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01)

Patent

CA 2584407

The invention provides a method for the isolation of haptoglobin from a sample comprising Cohn fraction V, wherein said method comprises anion exchange chromatography of said sample. The product may be further purified and/or subjected to one or more virus inactivation or reduction steps. The isolated haptoglobin may then be formulated for pharmaceutical use.

L'invention concerne un procédé qui permet d'isoler l'haptoglobine d'un prélèvement contenant une fraction V de Cohn, lequel procédé consiste à soumettre ledit prélèvement à une chromatographie par échange d'anions. Le produit peut être soumis à une purification supplémentaire et/ou à une ou plusieurs étapes d'inactivation ou de réduction virale. L'haptoglobine isolée peut alors être formulée en vue de son usage pharmaceutique.

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