Method for the manufacture of...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 229/00 (2006.01) C07C 261/00 (2006.01) C07C 271/00 (2006.01)

Patent

CA 2538175

The present invention relates to a new and efficient process for the manufacture of L-Threonine-O-(1,1-dimethylethyl) ester; [H-Thr-(tBu)-O-tBu] of Formula (I). The compound of Formula (I) is a key product for the manufacture of human insulin from porcine or bovine insulin.

La présente invention se rapporte à un procédé nouveau et efficace de production de l'ester de L-thréonine-O-(1,1-diméthyléthyl)-1,1-diméthyléthyle; [H-Thr-(tBu)-O-tBu] selon la formule I. Le composé selon la formule I est un produit clé dans la fabrication de l'insuline humaine à partir de l'insuline porcine ou bovine.

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